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Presentation
Evaluation of the use of an injectable matrix for tissue engineering of dental pulp
89th General Session & Exhibition of the IADR
  • Bruno Das Neves Cavalcanti, University of Michigan School of Dentistry
  • Benjamin David Zeitlin, University of the Pacfic
  • Jacques E. Nör, University of Michigan School of Dentistry
ORCiD
Dr. Benjamin D. Zeitlin: 0000-0003-0110-0188
Document Type
Conference Presentation
Organization
Brazilian Regional Division of IADR
Location
Brazil
Conference Dates
December 03-06, 2011
Date of Presentation
12-5-2011
Abstract
Dental pulp is a highly specialized mesenchymal tissue, which have a restrict regeneration capacity due to anatomical arrangement and post-mitotic nature of odontoblastic cells. Entire pulp amputation followed by pulp-space disinfection and filling with an artificial material cause loss of a significant amount of dentin leaving as life-lasting sequelae a non-vital and weakened tooth. However, regenerative endodontics is an emerging field of modern tissue engineering that demonstrated promising results using stem cells associated with scaffolds and responsive molecules. Thereby, this article will review the most recent endeavors to regenerate pulp tissue based on tissue engineering principles and providing insightful information to readers about the different aspects enrolled in tissue engineering. Here, we speculate that the search for the ideal combination of cells, scaffolds, and morphogenic factors for dental pulp tissue engineering may be extended over future years and result in significant advances in other areas of dental and craniofacial research. The finds collected in our review showed that we are now at a stage in which engineering a complex tissue, such as the dental pulp, is no longer an unachievable and the next decade will certainly be an exciting time for dental and craniofacial research.
Comments
First prize poster in the Endodontics and Pulp Biology Section
Citation Information
Bruno Das Neves Cavalcanti, Benjamin David Zeitlin and Jacques E. Nör. "Evaluation of the use of an injectable matrix for tissue engineering of dental pulp" 89th General Session & Exhibition of the IADR (2011)
Available at: http://works.bepress.com/benjamin-zeitlin/19/