|2014 - Present||Associate Professor, Nova Southeastern University ‐ Halmos College of Natural Sciences and Oceanography - Department of Chemistry and Physics|
|2009 - 2014||Assistent Professor, Nova Southeastern University|
|2008 - 2009||Instructor, Nova Southeastern University|
|1998 - 2004||General Chemistry Laboratory Coordinator, Florida Atlantic University|
|2004 - 2008||Ph.D., Chemistry, Florida Atlantic University|
|1996 - 1998||M.S.T., Teaching with a major in Chemistry, Florida Atlantic University|
|1992 - 1997||B.S. and B.A., Chemistry and Education, Jozsef Attila University Szeged|
Journal articles written or co-written by Dr. Beatrix Aukszi.
Antagonistic Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Reveal GRK5-Mediated Cardioprotection via Mineralocorticoid Receptor Inhibition International Journal of Molecular Sciences (2020)
Aldosterone (Aldo), when overproduced, is a cardiotoxic hormone underlying heart failure and hypertension. Aldo exerts damaging effects via the mineralocorticoid receptor (MR) but also activates the antiapoptotic G protein-coupled estrogen receptor (GPER) in the heart. ...
The Place of ARBs in Heart Failure Therapy: Is Aldosterone Suppression the Key? Therapeutic Advances in Cardiovascular Disease (2019)
Since the launch of the first orally available angiotensin II (AngII) type 1 receptor (AT1R) blocker (ARB) losartan (Cozaar) in the late 1990s, the class of ARBs (or ‘sartans’, short for Angiotensin-RecepTor-ANtagonistS) quickly expanded to ...
Differential Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Chemistry and Physics Faculty Proceedings, Presentations, Speeches, Lectures (2017)
Background: Heart failure (HF) is the leading cause of death in the western world and new and innovative treatments are urgently needed. Aldosterone (Aldo) is one of several cardio-toxic hormones, whose levels are increased in ...
Angiotensin Receptor Blocker Drugs and Inhibition of Adrenal Beta-Arrestin-1-Dependent Aldosterone Production: Implications for Heart Failure Therapy World Journal of Cardiology (2017)
Aldosterone mediates many of the physiological and pathophysiological/cardio-toxic effects of angiotensin II (AngII). Its synthesis and secretion from the zona glomerulosa cells of the adrenal cortex, elevated in chronic heart failure (HF), is induced by ...
Glycosylation Modulates Melanoma Cell α2β1 and α3β1 Integrin Interactions with Type IV Collagen Journal of Biological Chemistry (2014)
Although type IV collagen is heavily glycosylated, the influence of this posttranslational modification on integrin binding has not been investigated. In the present study, galactosylated and non-galactosylated triple-helical peptides have been constructed containing the α1(IV)382-393 ...
Modulation of Tumor Progression by Glycosylated Triple-helical Ligands FASEB Journal (2006)
Specific tumor cell interactions with basement membrane (type IV) or fibrillar (types I–III) collagen have been shown previously to represent a regulatory step in metastasis [Nat. Rev. Cancer3, 422 (2003)]. Interestingly, numerous tumor cell receptors, ...
Stereoselective Synthesis of Some Novel Heterocyclic Estrone Derivatives by Intramolecular 1,3-Dipolar Cycloaddition Tetrahedron (2002)
16,17-seco-3-Methoxyestra-1,3,5(10),16-tetraen-17-al undergoes intramolecular nitrone 1,3-dipolar cycloaddition with both hydroxylamine and N-methylhydroxylamine to produce a single isoxazolidine isomer in each case. The ring-closures of the hydrazones and the aldazine derived from the secoaldehyde lead to fused ...
3-Methoxy-1'-phenyl-4'[beta],5-dihydro-1H-pyrazolo[4',3':16,17]estra-1,3,5(10)-triene Acta Crystallographica Section E: Crystallographic Communications (2002)
The regio- and stereochemistry of the title compound, C26H30N2O, has been established by X-ray analysis. The configuration of the stereogenic centre at C-16 proved to be S and the H atom at C-16 adopts the ...
Books and Book Contributions (5)
Book and book contributions written or co-written by Dr. Beatrix Aukszi.
Conference presentations, proceedings, lectures, and symposia given by Dr. Beatrix Aukszi.
Guided Inquiry: Synthetic Investigation of Aromatic Systems Chemistry and Physics Faculty Proceedings, Presentations, Speeches, Lectures (2014)
The focus of this investigation is to aid the development of a new advanced synthetic organic chemistry course, aiming for the development of possible synthetic routes of aromatic systems. Through a guided inquiry approach, students ...
Complete Synthesis of Carbonyl-Containing Compounds: A Guided Inquiry Approach Chemistry and Physics Faculty Proceedings, Presentations, Speeches, Lectures (2014)
A new, upper level synthetic organic chemistry course is being developed utilizing a guided inquiry approach. This particular project is focused on developing the potential library of target carbonyl compounds and corresponding simple starting molecules.Figure ...
Complete Protection and Glycosylation of 5-Hydroxy-DL-Lysine Chemistry and Physics Faculty Proceedings, Presentations, Speeches, Lectures (2012)
Adiponectin, a protein hormone, has been shown to play a role in preventing the development of atherosclerosis, a common cardiovascular disease. Altering some of the amino acids in adiponectin can provide beneficial effects towards that ...
Total Synthesis of Functionalized Acenes Chemistry and Physics Faculty Proceedings, Presentations, Speeches, Lectures (2012)
Research project focused on preparation of acene dinitriles from benzene 1,2-dicarbaldehyde. A Wittig reagent of fumaronitrile and triethylphosphine yielded a new C-C double. The increased acidity of the a-H, between the new alkene bond and ...