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Article
Are statins associated with decreased tooth loss in chronic periodontitis
Meyers Primary Care Institute Publications and Presentations
  • Barry G. Saver, University of Massachusetts Medical School
  • Philippe P. Hujoel, University of Washington
  • Joana Cunha-Cruz, University of Washington
  • Gerardo Maupome, Indiana University School of Dentistry
UMMS Affiliation
Meyers Primary Care Institute; Department of Family Medicine and Community Health
Date
3-1-2007
Document Type
Article
Medical Subject Headings
Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Chronic Disease; Dental Care; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Periodontitis; Smoking; Tooth Loss
Abstract
AIM: To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis. MATERIAL AND METHODS: We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models. RESULTS: Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use. CONCLUSIONS: Statin use was not associated with either a decreased or an increased risk of tooth loss.
Comments

Citation: J Clin Periodontol. 2007 Mar;34(3):214-9. Epub 2007 Jan 25. Link to article on publisher's site

Related Resources
Link to Article in PubMed
PubMed ID
17257156
Citation Information
Barry G. Saver, Philippe P. Hujoel, Joana Cunha-Cruz and Gerardo Maupome. "Are statins associated with decreased tooth loss in chronic periodontitis" Vol. 34 Iss. 3 (2007) ISSN: 0303-6979 (Linking)
Available at: http://works.bepress.com/barry_saver/33/