Skip to main content
Article
Nanoscale morphology of polyanhydride copolymers
Macromolecules
  • Matthew J. Kipper, Iowa State University
  • Sheng-Shu Hou, Iowa State University
  • Soenke Seifert, Argonne National Laboratory
  • Papannan Thiyagarajan, Argonne National Laboratory
  • Klaus Schmidt-Rohr, Ames Laboratory
  • Balaji Narasimhan, Iowa State University
Document Type
Article
Publication Date
1-1-2005
DOI
10.1021/ma051267r
Abstract

The microphase separation in polyanhydride random copolymers composed of 1,6-bis(p-carboxyphenoxy)hexane and sebacic acid is described. Though the copolymers are random, the monomers are sufficiently long and the segment-segment interaction parameter is sufficiently high to promote microphase separation when the copolymer is rich in one component. Solid-state NMR spin diffusion experiments and synchrotron small-angle X-ray scattering are used to discern the length scales of the microphase separation. Both techniques reveal a nanostructure with domain sizes less than 25 Ã…. This nanostructure is compared to approximate calculations of chain dimensions based on a random coil model and discussed in the context of the rational design of these materials for drug delivery applications.

Comments

Reprinted (adapted) with permission from Macromolecules 38 (2005): 8468, doi: 10.1021/ma051267r. Copyright 2005 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
Date Available
2015-02-03
File Format
application/pdf
Citation Information
Matthew J. Kipper, Sheng-Shu Hou, Soenke Seifert, Papannan Thiyagarajan, et al.. "Nanoscale morphology of polyanhydride copolymers" Macromolecules Vol. 38 Iss. 20 (2005) p. 8468 - 8472
Available at: http://works.bepress.com/balaji_narasimhan/14/