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Article
Prevalence and significance of vitamin D deficiency and insufficiency among apparently healthy adults
Clinical Biochemistry
  • Shireen Mansoor, Aga Khan University
  • Aysha Habib Khan, Aga Khan University
  • Farooq Ghani, Aga Khan University
  • Zafar Fatmi, Aga Khan University
  • Salma Badruddin, Aga Khan University
  • Sarwat Mansoor, Aga Khan University
  • Imran Siddiqui, Aga Khan University
  • Abdul Jabbar, Aga Khan University
Publication Date
12-1-2010
Document Type
Article
Abstract
Objective: This study aims to determine the prevalence and significance of vitamin D deficiency and insufficiency among apparently healthy adults. Design and methods: A total of 123 subjects, 56.9% males and 43.1% females, were recruited from a tertiary care hospital in Karachi, Pakistan. Questionnaires were administered to gather demographics, height, weight, and blood samples were also taken. For staging serum 25OHD, the cutoff values Results:The mean vitamin D level in the study subjects was 41.1 +/- 9.6 nmol/L. Of them, 90% had low serum 25OHD levels: 69.9% were deficient and 21.1% had insufficient levels of 25OHD. There was a significant negative correlation between serum 25OHD and iPTH levels. Conclusion: The high prevalence of vitamin D deficiency and insufficiency showed that a high proportion of apparently healthy adults are at risk of developing musculoskeletal and other chronic diseases. Serum iPTH and serum 25OHD levels are better markers of this deficiency as compared to other markers.
Citation Information
Shireen Mansoor, Aysha Habib Khan, Farooq Ghani, Zafar Fatmi, et al.. "Prevalence and significance of vitamin D deficiency and insufficiency among apparently healthy adults" Clinical Biochemistry Vol. 43 Iss. 18 (2010) p. 1431 - 1435
Available at: http://works.bepress.com/aysha_habib/31/