|Present||Chair and Professor, Philadelphia College of Osteopathic Medicine ‐ Department of Pharmaceutical Sciences|
- Cardiovascular Physiology
Scholarly Articles (74)
Metalloendopeptidase inhibition regulates phosphorylation of p38-mitogen-activated protein kinase and nitric ...
Shock (Augusta, Ga.) (2003)
We tested the hypothesis that metalloendopeptidase inhibition using phosphoramidon during induction of endotoxemia 24 h later would down-regulate the protein ...
Decompensation characterized by decreased perfusion of the heart and brain ...
Journal of Trauma - Injury, Infection and Critical Care (2002)
Background: Endothelin-1 (ET-1), a 21-amino-acid peptide produced by vascular endothelium, is a potent vasoconstrictor and a component of local regulation ...
Role of et and NO in resuscitative effect of diaspirin ...
American Journal of Physiology - Heart and Circulatory Physiology (1997)
Diaspirin cross-linked hemoglobin (DCLHb) is a hemo-globin-based therapeutic agent that produces significant cardiovascular effects, possibly due to its actions on ...
Role of endothelin in the cardiovascular effects of diaspirin crosslinked ...
Critical Care Medicine (1996)
Objectives: Diaspirin crosslinked hemoglobin is a resuscitative solution with excellent oxygen-carrying capacity. Diaspirin crosslinked hemoglobin produces an immediate increase in ...