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Article
Possible maternal inheritance of a common obstructive urinary tract anomaly. Report of a case of a woman with multiple urinary tract infections and two sons with posterior urethral valves
The Journal of reproductive medicine
  • D. G. Trembath
  • Asha Rijhsinghani, University of Iowa
Document Type
Article
Peer Reviewed
1
Publication Date
11-1-2002
NLM Title Abbreviation
J Reprod Med
PubMed ID
12497693
Abstract

BACKGROUND: Posterior urethral valves (PUVs) are the most common cause of lower urinary tract obstruction in boys. Several prior reports have described PUV in siblings and twins, often with a variable phenotype. CASE: PUVs were found in two brothers. The first child had developmental delay, while the second had a branchial cleft cyst and an anteriorly rotated right ear. The children's mother had a history of numerous urinary tract infections of unknown etiology. CONCLUSION: Though most cases of PUV appear to be sporadic, there are reports that suggest a partial genetic etiology, as our case suggests.

Keywords
  • Abnormalities,
  • Multiple/diagnosis/genetics/pathology/ultrasonography,
  • Adult,
  • Female,
  • Humans,
  • Infant,
  • Newborn,
  • Male,
  • Siblings,
  • Ultrasonography,
  • Prenatal,
  • Urethra/abnormalities/ultrasonography,
  • Urethral Obstruction/complications/diagnosis/genetics/pathology/ultrasonography,
  • Urinary Tract Infections/etiology
Published Article/Book Citation
The Journal of reproductive medicine, 47:11 (2002) pp.962-964.
Citation Information
D. G. Trembath and Asha Rijhsinghani. "Possible maternal inheritance of a common obstructive urinary tract anomaly. Report of a case of a woman with multiple urinary tract infections and two sons with posterior urethral valves" The Journal of reproductive medicine Vol. 47 Iss. 11 (2002) p. 962 - 964 ISSN: 0024-7758
Available at: http://works.bepress.com/asha_rijhsinghani/24/