© 2017 IEEE. Bone suppression in lung radiographs is an important task, as it improves the results on other related tasks, such as nodule detection or pathologies classification. In this paper, we propose two architectures that suppress bones in radiographs by treating them as noise. In the proposed methods, we create end-to-end learning frameworks that minimize noise in the images while maintaining sharpness and detail in them. Our results show that our proposed noise-cancellation scheme is robust and does not introduce artifacts into the images.