Article
Self-Immolative Aryl Phthalate Esters
The Journal of Organic Chemistry
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
1-1-2013
DOI
10.1021/jo301698v
Abstract
We report that aryl phthalate esters are robust self-immolative linkers. This linker is easy to conjugate and releases output phenols upon cleaving a fluoride-sensitive mask to yield a benign phthalic acid byproduct, making these linkers potentially useful as fluoride sensors and promising for use in biological and materials applications.
Copyright Owner
American Chemical Society
Copyright Date
2012
Language
en
File Format
application/pdf
Citation Information
Kaitlyn M. Mahoney, Pratik P. Goswami and Arthur Winter. "Self-Immolative Aryl Phthalate Esters" The Journal of Organic Chemistry Vol. 78 Iss. 2 (2013) p. 702 - 705 Available at: http://works.bepress.com/arthur_winter/9/
Reprinted (adapted) with permission from J. Org. Chem., 2013, 78 (2), pp 702–705. Copyright 2012 American Chemical Society.