N-methyl-d-aspartate channel and consciousness: from signal coincidence detection to quantum computingProgress in Neurobiology (2001)
AbstractResearch on Blindsight, Neglect/Extinction and Phantom limb syndromes, as well as electrical measurements of mammalian brain activity, have suggested the dependence of vivid perception on both incoming sensory information at primary sensory cortex and reentrant information from associative cortex. Coherence between incoming and reentrant signals seems to be a necessary condition for (conscious) perception. General reticular activating system and local electrical synchronization are some of the tools used by the brain to establish coarse coherence at the sensory cortex, upon which biochemical processes are coordinated. Besides electrical synchrony and chemical modulation at the synapse, a central mechanism supporting such a coherence is the N-methyl-d-aspartate channel, working as a ‘coincidence detector’ for an incoming signal causing the depolarization necessary to remove Mg2+, and reentrant information releasing the glutamate that finally prompts Ca2+ entry. We propose that a signal transduction pathway activated by Ca2+ entry into cortical neurons is in charge of triggering a quantum computational process that accelerates inter-neuronal communication, thus solving systemic conflict and supporting the unity of consciousness.
- Quantum computing,
- Brain processing,
Citation InformationArmando F Rocha and Alfredo Pereira. "N-methyl-d-aspartate channel and consciousness: from signal coincidence detection to quantum computing" Progress in Neurobiology (2001)
Available at: http://works.bepress.com/armando_rocha/18/