Some children with chronic lung diseases (CLD) may require home mechanical ventilation (HMV). This section will focus on bronchopulmonary dysplasia (BPD) and cystic fibrosis (CF), though other CLDs such as primary ciliary dyskinesia and those that may result in pulmonary hypertension are also addressed.1,2 The goals of this section are: (1) to review the literature on the experience in using HMV (invasive and noninvasive) in children with chronic respiratory failure secondary to CLD such as BPD and CF; (2) to review the outcomes of HMV for these populations; (3) to provide Canadian-specific pediatric practice recommendations around long-term home ventilation for children with respiratory failure and hypoventilation secondary to CLD; and (4) to identify areas for further research.