Aerodynamic noise produced by aerodynamic interaction between a cylinder (rod) and an airfoil in tandem arrangement is investigated using large eddy simulations. Wake from the rod convects with the flow, impinges of the airfoil to produce unsteady force which acts as a sound source. This rod-airfoil interaction problem is a model problem for noise generation due to inflow or upstream-generated turbulence interacting with a turbomachine bladerow or a wind turbine rotor. The OpenFoam and Charles (developed by Cascade Technologies) solvers are chosen to carry out the numerical simulations. The airfoil is set at zero angle of attack for the simulations. The flow conditions are specified by the Reynolds number (based on the rod diameter), Red = 48 K, and the flow Mach number, M = 0.2. Comparisons with measured data are made for (a) mean and root-mean-squared velocity profiles in the rod and airfoil wakes, (b) velocity spectra in the near field, and (c) far-field pressure spectra and directivity. Near-field flow data (on- and off-surface) is used with the Ffowcs Williams-Hawkings (FW-H) acoustic analogy as well as Amiet’s theory to predict far-field sound.