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Article
Effect of age on the frequency of anxiety disorders in major depression with psychotic features
Psychiatry Publications and Presentations
  • Alastair J. Flint, University of Toronto
  • Catherine Peasley-Miklus, Cornell University
  • Eros Papademetriou, Weill Medical College
  • Barnett S. Meyers, Cornell University
  • Benoit H. Mulsant, University of Toronto
  • Anthony J. Rothschild, University of Massachusetts Medical School
  • Ellen M. Whyte, University of Pittsburgh
UMMS Affiliation
Department of Psychiatry
Publication Date
4-30-2010
Document Type
Article
Subjects
Adult; Age Factors; Aged; Anxiety Disorders; Depressive Disorder, Major; Female; Humans; Prevalence; Psychotic Disorders
Disciplines
Abstract
OBJECTIVE: To compare the frequency of anxiety disorders in older and younger persons with major depressive disorder with psychotic features. DESIGN: Cross-sectional. SETTING: University medical centers. PARTICIPANTS: Two hundred fifty-nine persons (N = 117 aged 18-59 years and N = 142 aged > or =60 years) with major depressive disorder with psychotic features who were enrolled in the Study of the Pharmacotherapy of Psychotic Depression (STOP-PD). MEASUREMENTS: Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, (DSM-IV) defined anxiety disorders were determined by Structured Clinical Interview for DSM-IV interview at baseline assessment. Younger and older participants were compared on the frequencies of any current anxiety disorder and any lifetime anxiety disorder, as well as the frequencies of individual anxiety disorders. RESULTS: Older persons had significantly lower frequencies of any current anxiety disorder and any lifetime anxiety disorder, even after controlling for relevant demographic and clinical variables. With respect to specific anxiety disorders, older persons had significantly lower frequencies of current and lifetime panic disorder, current and lifetime social anxiety disorder, and current and lifetime posttraumatic stress disorder. CONCLUSION: The findings of this study are consistent with those of community-based epidemiologic surveys that anxiety disorders are less prevalent in older than younger adults. Because of the rigorous assessment used in STOP-PD, our findings suggest that the age-related decline in the prevalence of anxiety disorders is not simply due to a failure to detect cases in older people, as has been previously suggested.
Source
Am J Geriatr Psychiatry. 2010 May;18(5):404-12.
Related Resources
Link to Article in PubMed
PubMed ID
20429084
Citation Information
Alastair J. Flint, Catherine Peasley-Miklus, Eros Papademetriou, Barnett S. Meyers, et al.. "Effect of age on the frequency of anxiety disorders in major depression with psychotic features" Vol. 18 Iss. 5 (2010) ISSN: 1064-7481 (Linking)
Available at: http://works.bepress.com/anthony_rothschild/106/