In the past decade an extensive experimental program to measure the spin structure of the nucleon has been carried out in the three halls at Jefferson Lab. Using a longitudinally polarized beam scattering off longitudinally or transversely polarized 3He, NH3 and ND3 targets, the double spin asymmetries A∥ and A⊥ were measured, providing data of impressively high precision that gives a better understanding of the structure of the nucleon in the deep inelastic scattering and the valence quarks regions. The virtual photon asymmetries A1,2 and polarized structure functions g1,2 were also extracted for the proton, neutron and deuteron over large kinematic ranges, allowing the extraction of first moments and the testing of sum rules and duality.