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Presentation
Variable diastereoselectivity in acylation of 2-substituted cyclohexanols
241st American Chemical Society (ACS) National Meeting & Exposition
  • Andrey V. Samoshin, University of the Pacific
  • Jasper Visser
  • Matthew Curtis, University of the Pacific
  • Andreas H. Franz, University of the Pacific
Document Type
Conference Presentation
Department
Chemistry
Organization
American Chemical Society (ACS)
Location
Anaheim, CA
Conference Dates
March 27-31, 2011
Date of Presentation
3-30-2011
Disciplines
Abstract
The ratio of diastereomeric products A and B in acylation of 2-substituted cyclohexanols was found to depend dramatically on the nature of substituents, solvent and additives. Unusual inversion of diastereoselectivity upon change of a solvent or addition of tertiary amines was found for certain combinations of reactants and conditions.
Citation Information
Andrey V. Samoshin, Jasper Visser, Matthew Curtis and Andreas H. Franz. "Variable diastereoselectivity in acylation of 2-substituted cyclohexanols" 241st American Chemical Society (ACS) National Meeting & Exposition (2011)
Available at: http://works.bepress.com/andreas-franz/88/