Variable diastereoselectivity in acylation of 2-substituted cyclohexanols241st American Chemical Society (ACS) National Meeting & Exposition
Document TypeConference Presentation
OrganizationAmerican Chemical Society (ACS)
Conference DatesMarch 27-31, 2011
Date of Presentation3-30-2011
AbstractThe ratio of diastereomeric products A and B in acylation of 2-substituted cyclohexanols was found to depend dramatically on the nature of substituents, solvent and additives. Unusual inversion of diastereoselectivity upon change of a solvent or addition of tertiary amines was found for certain combinations of reactants and conditions.
Citation InformationAndrey V. Samoshin, Jasper Visser, Matthew Curtis and Andreas H. Franz. "Variable diastereoselectivity in acylation of 2-substituted cyclohexanols" 241st American Chemical Society (ACS) National Meeting & Exposition (2011)
Available at: http://works.bepress.com/andreas-franz/88/