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Article
Synthesis and characterization of biotin derivatives as multifunctional oligosaccharide tags
ARKIVOC
  • Nandkishor S. Chindarkar
  • Andreas H. Franz, University of the Pacific
Document Type
Article
Department
Chemistry
DOI
10.3998/ark.5550190.0009.f03
Publication Date
1-1-2008
Disciplines
Abstract
The synthesis of novel multifunctional oligosaccharide tags with amino, azido, and alkyne termini is described. Tags with an amino terminus can be introduced into the carbohydrate at the reducing end through reductive amination, while 1,3-dipolar cycloaddition (“click chemistry”) can be used to label azido sugars with oligosaccharide tags having an alkyne terminus and vice versa.
Creative Commons License
Creative Commons Attribution 4.0
Citation Information
Nandkishor S. Chindarkar and Andreas H. Franz. "Synthesis and characterization of biotin derivatives as multifunctional oligosaccharide tags" ARKIVOC Vol. 2008 Iss. 15 (2008) p. 21 - 33 ISSN: 1551-7012
Available at: http://works.bepress.com/andreas-franz/71/