Non-covalent calixarene–amino acid complexes formed by MALDI-MSJournal of the American Society for Mass Spectrometry
AbstractNon-covalent inclusion complexes formed between amino acids and derivatized calixarenes are observed in MALDI mass spectrometry. The methyl, ethyl, and propyl ester derivatives of calixarene yielded amino acid complexes, while the smaller calixarene analogs did not. Similarly the underivatized calixarene and calixarene did not produce complexes. Amino acid complexes were observed for nearly all 20 amino acids in time-of-flight (TOF) analysis. In Fourier transform mass spectrometry (FTMS) analysis, however, only the most basic amino acids arginine, histidine, and lysine formed stable adducts. The complexes were abundant under matrix-assisted laser desorption ionization (MALDI) conditions, which suggested favorable interactions between host and guest.
Citation InformationMichele M. Stone, Andreas H. Franz and Carlito B. Lebrilla. "Non-covalent calixarene–amino acid complexes formed by MALDI-MS" Journal of the American Society for Mass Spectrometry Vol. 13 Iss. 8 (2002) p. 964 - 974 ISSN: 1044-0305
Available at: http://works.bepress.com/andreas-franz/26/