Blockchain technology has the potential to impact the performance of small-and-medium enterprises (SMEs). A theoretical model using Technology-Organization-Environment framework and Resource-based View was developed to examine Blockchain-driven SME business performance. The model was empirically tested using structural equation modeling techniques on data gathered from 320 practitioners in Nigeria, Ghana and Kenya. The technological and organizational contexts for Blockchain influenced organizational commitment while top management support for Blockchain influenced organizational transparency, both of which influenced Smart SMEs resulting in enhanced performance. Social media visibility moderated the effect of Smart SMEs on performance. The findings offer several implications for research and practice.