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Vitamin d deficiency in cystic fibrosis
International journal of endocrinology
  • W. B. Hall
  • Amy E.T. Sparks, University of Iowa
  • R. M. Aris
Document Type
Peer Reviewed
Publication Date
NLM Title Abbreviation
Int J Endocrinol
PubMed ID
DOI of Published Version
Cystic Fibrosis is the most common inherited genetic respiratory disorder in the Western World. Hypovitaminosis D is almost universal in CF patients, likely due to a combination of inadequate absorption, impaired metabolism, and lack of sun exposure. Inadequate levels are associated with the high prevalence of bone disease or osteoporosis in CF patients, which is associated with increased morbidity including fractures, kyphosis, and worsening pulmonary status. Treatment goals include regular monitoring 25 hydroxyvitamin D (25OHD) levels with aggressive treatment for those with levels <75 nmol/L (<30 ng/mL). More research is needed to determine optimal supplementation goals and strategies.
Published Article/Book Citation
International journal of endocrinology, 2010 (2010) pp.218691
Citation Information
W. B. Hall, Amy E.T. Sparks and R. M. Aris. "Vitamin d deficiency in cystic fibrosis" International journal of endocrinology Vol. 2010 (2010) p. 218691 ISSN: 1687-8345
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