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Article
Development of an immunocontraceptive vaccine. Current status
The Journal of reproductive medicine
  • H. Feng
  • J. I. Sandlow
  • Amy E.T. Sparks, University of Iowa
  • A. Sandra
Document Type
Article
Peer Reviewed
1
Publication Date
9-1-1999
NLM Title Abbreviation
J Reprod Med
PubMed ID
10509297
Abstract

Development of an effective and modern contraceptive vaccine is a key factor in the global issue of regional population growth as well as agricultural, medical, economic and social development. A review was done of the current medical literature concerning development of an immunocontraceptive vaccine and relative molecular biology technology. Various approaches have been taken to identify candidate-specific antigens for immunocontraceptive development, such as sperm, zona pellucida and hormonal antigens. Suppressed fertility and the reversibility of these effects on mammalian species, including humans, have been demonstrated. The successful results obtained so far support the continued investigation for an effective immunocontraceptive vaccine.

Keywords
  • Animals,
  • Antigens/immunology,
  • Contraception,
  • Immunologic,
  • Female,
  • Hormones/immunology,
  • Humans,
  • Male,
  • Spermatozoa/immunology,
  • Vaccines,
  • Zona Pellucida/immunology
Published Article/Book Citation
The Journal of reproductive medicine, 44:9 (1999) pp.759-765.
Citation Information
H. Feng, J. I. Sandlow, Amy E.T. Sparks and A. Sandra. "Development of an immunocontraceptive vaccine. Current status" The Journal of reproductive medicine Vol. 44 Iss. 9 (1999) p. 759 - 765 ISSN: 0024-7758
Available at: http://works.bepress.com/amy_sparks/64/