Federal relief funds distributed during the Great Depression provided unprecedented support for archaeology in the United States, resulting in a new understanding of Native American lifeways in the Southeast. Ultimately, these funds led to robust archaeological studies in the state of Louisiana and the establishment of an interdisciplinary Department of Geography and Anthropology at Louisiana State University (LSU). The knowledge gained from excavations was shared with the public via the creation of a museum, affectionately known as the Indian Room, housed in the Department of Geography and Anthropology. In this article, we relate the story of the development of the museum, answering a growing call in the discipline to pay more attention to museum geographies. Utilizing the disorderly archive approach of Hayden Lorimer and Chris Philo, we also discuss how the depression-relief projects led to the emergence of professional archaeology, the resultant formation of a department at Louisiana State University, and the ongoing transformation of the museum.