ABSTRACT Stigma and discrimination continue to be a reality in the lives of people suffering from mental illness, particu- larly schizophrenia, and prove to be some of the greatest barriers to access care, continue to remain under care, and regain a normal lifestyle and health. Research advances have defined stigma, assessed its implications and have even examined intervention strategies for dealing with stigma. The delay in treatment due to stigma causes potential complications like suicide, violence, harm to others and deterioration in capacity to look after one’s physical health. These are preventable clinical complications. In order to deal with the impact of stigma on an individual basis, it needs to be [1] assessed during routine clinical examination, [2] assessed for quantification in order to obtain measurable objective deliv- erables, and [3] examined if treatment can reduce stigma and its impact on individuals. We are of the opinion that stigma has several domains: personal, social, cultural, illness-related, treatment-related, and environmental. Each of these domains has several factors, which may or may not contribute to the degree of stigma affecting a given individual. Components of these domains can be used to design a tool, which can then be standardized and validated in controlled studies. Quantify- ing stigma in terms of its impact and consequences requires attention to four different components: 1) events of discrimina- tion that have taken place, 2) the real-life experience, 3) the patients’ perception of this discrimination, and 4) how has the patient coped to live with discrimination. A reasonable quantification of stigma would be to measure the consequences and its perception in an individual. We hypothesize that the efficacy of an intervention can be successfully measured by comparing it before and after treatment.Longer durations of illness, and particularly treatment, were associated with fewer consequences of stigma and discrimination. Higher levels of consequences related to stigma and discrimination were found to relate to a greater likelihood of non-compliance and to a greater risk for suicide. By assessing and quantifying stigma in this way, there is a better chance of these consequences being reduced and addressed