With funding from check-off dollars from the Iowa Soybean Association, we have evaluated the effect of commercially available fungicide and insecticide seed treatments. We evaluated seedling diseases, insects, and yield of soybean in Iowa in 2012. This field study was done at three locations in Iowa: ISU Northeast Research and Demonstration Farm (NERF), Nashua; ISU Southeast Research and Demonstration Farm (SERF) near Crawfordsville; and a farmer’s field in Nevada (two planting dates). Soybean variety varied by location. Seed treatments were professionally applied by the respective companies. Varieties are commercially available, but their information will not be disclosed.