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RAC/ROP GTPases: 'hubs' for signal integration and diversification in plants
Trends in Plant Science (2006)
  • C. Nibau
  • H. M. Wu
  • Alice Cheung, University of Massachusetts - Amherst
RAC/ROP GTPases are a family of plant-specific signaling molecules solely representing the Ras and Rho family of Ras-related G proteins in plants. RAC/ROPs potentially interact with cell surface-associated signal perception apparatus for a broad range of extracellular stimuli, including hormones, pathogen elicitors and abiotic stress, and mediate diverse cellular pathways in response to these signals. They are also known to interact with multiple effectors, affecting cellular and biochemical systems that regulate actin dynamics, reactive oxygen species production, proteolysis, and gene expression. RAC/ROPs are, thus, ideally suited as integrators for multiple signals and as coordinators of diverse cellular pathways to control growth, differentiation, development and defense responses. Recent findings that suggest how RAC/ROP signaling activity is regulated and how functional specificity can be achieved are discussed here.
Publication Date
June, 2006
Publisher Statement
Citation Information
C. Nibau, H. M. Wu and Alice Cheung. "RAC/ROP GTPases: 'hubs' for signal integration and diversification in plants" Trends in Plant Science Vol. 11 Iss. 6 (2006)
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