Other
Saccharide conjugates
(2015)
Abstract
The invention provides a series of novel Lipid A analogs that are structurally simple, synthetically accessible, and capable of blocking the cellular receptor within the signal transduction pathway. The novel Lipid A analogs can include a monosaccharide core with hydrophobic side chains and amino acid ionic motif. The invention further provides methods of using the compounds and compositions thereof in various therapeutic methods.
Disciplines
Publication Date
September 1, 2015
Comments
Patent Number
US9120838B2
Citation Information
Alexei Demchenko, Michael R. Nichols and Sophon Kaeothip. "Saccharide conjugates" (2015) Available at: http://works.bepress.com/alexei-demchenko/182/