The purpose of this document is to serve as a reference for individuals involved in the swine industry to understand steps which can be taken to mitigate the risk of disease transmission. Biological risk management (BRM) is essential to all swine operations regardless of their size or mode of operation. Disease risk can never be completely eliminated. A full awareness of all risks is critical in mitigating threats of endemic, emerging, and foreign animal diseases. This document illustrates the best available “standard operating procedures” for a wide range of management practices. This is a working document that needs to be adjusted as new information is available.