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The REFLECT Statement: Methods and Processes of Creating Reporting Guidelines For Randomized Controlled Trials for Livestock and Food Safety
Preventive Veterinary Medicine
  • Annette M. O'Connor, Iowa State University
  • Jan M. Sargeant, University of Guelph
  • I. A. Gardner, University of California - Davis
  • James S. Dickson, Iowa State University
  • Mary E. Torrence, United States Department of Agriculture
  • C. E. Dewey, University of Guelph
  • Ian R. Dohoo, University of Prince Edward Island
  • R. B. Evans, University of Illinois at Urbana-Champaign
  • J. T. Gray, Des Moines University
  • Mattias Greiner, Federal Institute for Risk Assessment
  • Greg Keefe, Atlantic Veterinary College University of Prince Edward Island
  • Sandra L. Lefebvre, American Veterinary Medical Association
  • Paul S. Morley, Colorado State University - Fort Collins
  • Alejandro Ramirez, Iowa State University
  • William Sischo, Washington State University
  • D. R. Smith, University of Nebraska-Lincoln
  • Kate Snedeker, University of Guelph
  • John N. Sofos, Colorado State University - Fort Collins
  • M. P. Ward, University of Sydney
  • Robert W. Wills, Mississippi State University College of Veterinary Medicine
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The conduct of randomized controlled trials in livestock with production, health, and foodsafety outcomes presents unique challenges that may not be adequately reported in trial reports. The objective of this project was to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A two-day consensus meeting was held on November 18–19, 2008 in Chicago, IL, United States of America, to achieve the objective. Prior to the meeting, a Web-based survey was conducted to identify issues for discussion. The 24 attendees were biostatisticians, epidemiologists, food-safety researchers, livestock-production specialists, journal editors, assistant editors, and associate editors. Prior to the meeting, the attendees completed a Web-based survey indicating which CONSORT statement items may need to be modified to address unique issues for livestock trials. The consensus meeting resulted in the production of the REFLECT (Reporting Guidelines For Randomized Control Trials) statement for livestock and food safety (LFS) and 22-item checklist. Fourteen items were modified from the CONSORT checklist, and an additional sub-item was proposed to address challenge trials. The REFLECT statement proposes new terminology, more consistent with common usage in livestock production, to describe study subjects. Evidence was not always available to support modification to or inclusion of an item. The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes.

This article is from Preventive Veterinary Medicine 93 (2010): 11, doi:10.1016/j.prevetmed.2009.10.008.

Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.
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Annette M. O'Connor, Jan M. Sargeant, I. A. Gardner, James S. Dickson, et al.. "The REFLECT Statement: Methods and Processes of Creating Reporting Guidelines For Randomized Controlled Trials for Livestock and Food Safety" Preventive Veterinary Medicine Vol. 93 (2010) p. 11 - 18
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