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Fungal endocarditis with severe vegetations of the aortic valve and septic emboli secondary to total parenteral nutrition
Cureus
  • Andrii Labchuk, Advocate Aurora Health
  • Mada Hamwi, Advocate Aurora Health
  • Alice Han, Advocate Aurora Health
  • Muhammad Khan, Advocate Aurora Health
  • Arvey Stone, Advocate Aurora Health
Affiliations

Advocate Lutheran General Hospital

Scholarly Activity Date
12-9-2022
Abstract

Fungal endocarditis is a rare but serious complication of fungemia. It is most commonly caused by Candida species. Risk factors include prosthetic heart valves, injection drug use, and indwelling central venous catheters. In comparison to bacterial endocarditis, fungal endocarditis is more commonly associated with arterial embolization, likely due to the larger size of vegetations. Unfortunately, diagnosis is often delayed, contributing to significant morbidity and mortality. Relapses are common, and extended treatment is often warranted. Antifungal agents and valve replacement are the recommended treatments. However, in-hospital mortality remains at 36%. For these reasons, it is critical to have a high index of suspicion and not delay appropriate therapy.

Type
Article
PubMed ID
36627999
Citation Information

Labchuk A, Hamwi M, Han A, Khan M, Stone A. Fungal Endocarditis With Severe Vegetations of the Aortic Valve and Septic Emboli Secondary to Total Parenteral Nutrition. Cureus. 2022;14(12):e32357. Published 2022 Dec 9. doi:10.7759/cureus.32357