Two professors from two disciplines—education and sociology—analyzed the commonalities, differences, successes, and challenges of conducting cross-disciplinary Scholarship of Teaching and Learning (SoTL) research at the course level (micro-level). This case study of their collaboration resulted in a series of lessons learned which add to the literature base on the process of SoTL collaboration. The results of their professional collaboration at this level provide a validation for increased communication and alignment during the development and implementation of the projects developed to enhance teaching and learning in their respective courses. This erudition illuminates the potential of increased SoTL collaborations across disciplines at the micro-level.