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Article
Effects of the Number and Placement of Positive Charges on Viologen–Cucurbit[n]uril Interactions
Supramolecular Chemistry
  • Gretchen A Vincil, Trinity University
  • Adam R Urbach, Trinity University
Document Type
Article
Publication Date
12-1-2008
Abstract

Recent developments in the synthesis and applications of the cucurbit[n]uril family of synthetic hosts has led to an increasing interest in the detailed studies of their interactions with a wide variety of guests. This paper describes a quantitative study of the effects of the number and placement of positive charges on the binding of viologen guests to cucurbit[7]uril and cucurbit[8]uril. A series of viologen derivatives with one to four charges was characterised by isothermal titration calorimetry, 1H NMR spectroscopy and mass spectrometry to determine the stoichiometry, affinity and mode of binding. These data show that stoichiometry can be controlled by the placement of charge, and that affinity can be increased by the addition of positive charges. This study should serve as a guide for the design of supramolecular structures built from viologens and cucurbit[n]urils.

Document Object Identifier (DOI)
10.1080/10610270701689572
Citation Information
Vincil, G. A., & Urbach, A. R. (2008). Effects of the number and placement of positive charges on viologen–cucurbit[n]uril interactions. Supramolecular Chemistry, 20, 681-687. doi: 10.1080/10610270701689572