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Article
A Cucurbit[8]uril Sponge
Organic and Biomolecular Chemistry
  • Vijayakumar Ramalingam, Trinity University
  • Sharon K Kwee, Trinity University
  • Lisa M Ryno, Trinity University
  • Adam R Urbach, Trinity University
Document Type
Post-Print
Publication Date
11-21-2012
Abstract

This paper describes a convenient approach to quantitative removal of the synthetic host cucurbit[8]uril (Q8) from aqueous mixtures using a sepharose resin coated in memantine groups to selectively sequester Q8 in the presence of competing hosts and guests. The “Q8 sponge” can separate Q8 from Q6 and reverse the Q8-mediated dimerization of peptides.

DOI
10.1039/C2OB26774H
Publisher
Royal Society of Chemistry
Citation Information
Ramalingam, V., Kwee, S. K., Ryno, L. M., & Urbach, A. R. (2012). A cucurbit[8]uril sponge. Organic and Biomolecular Chemistry, 10(43), 8587-8589. https://doi.org/10.1039/c2ob26774h