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Opioid Antagonists: Will they Solve all of the Problems Associated with Opioid Agonists?
Global Journal of Anesthesiology
  • Adam M. Kaye, University of the Pacific
ORCiD
Adam M. Kaye: 0000-0002-7224-3322
Document Type
Article
DOI
10.17352/2455-3476.000002
Publication Date
8-13-2014
Abstract

Physicians employed in operating and emergency rooms have utilized opioid antagonist for almost half a century for the treatment of opioid overdose. The prototype antagonist remains naloxone hydrochloride, which actually received FDA approval back in 1971. Why after so many years on the market is this medication now being formulated in the form of an easy to use “auto-injector” that was designed for non-medical professionals to be able to utilize at a moment's notice? Could this wonder product, being hailed as the best possible safety tool available for life threatening opioid emergencies actual make heroes out of lay people? [1].

Will marketing and providing to the family and caregivers of chronic pain patients prevent the epidemic of opioid medication related deaths of people in our country? What else can be done by physicians and the U.S. Food and Drug Administration (FDA) to reduce the unbelievable statistic of a death every 36 minutes from an opioid overdose in the United States? With upwards of 17,000 Americans dying yearly from prescription opioid overdose, accidently or intentionally via suicide& deliberate misuse, and constantly consuming more and more of these powerful painkillers-the million dollar question remaining to be answered is: will a new drug formulation device in the hands of laypeople really make a dent in this crisis that in recent years has actually surpassed car accidents as the leading cause of accidental death? [2].

Creative Commons License
Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International
Citation Information
Adam M. Kaye. "Opioid Antagonists: Will they Solve all of the Problems Associated with Opioid Agonists?" Global Journal of Anesthesiology Vol. 1 Iss. 1 (2014) p. 9 - 12 ISSN: 2455-3476
Available at: http://works.bepress.com/adam-kaye/97/