Article
Brexanolone to Treat Postpartum Depression in Adult Women.
Psychopharmacology Bulletin
ORCiD
Adam M. Kaye: 0000-0002-7224-3322
Document Type
Article
Publication Date
3-16-2021
Disciplines
Abstract
ZULRESSO (Brexanolone) is a novel FDA-approved treatment for moderate-to-severe postpartum depression. Postpartum depression may be diagnosed in women experiencing depressive symptoms which can manifest as cognitive, behavioral, or emotional disturbances as early as the third trimester to 4 weeks following delivery. The efficacy of brexanolone suggests that neurosteroids such as allopregnanolone are important to treat PPD. However, it is currently unclear if brexanolone provides lasting relief of depressive symptoms at or beyond 30 days following administration. Further studies are necessary to make this determination.
Citation Information
Elyse M. Cornett, Lauren Rando, Austin M. Labbé, Wil Perkins, et al.. "Brexanolone to Treat Postpartum Depression in Adult Women." Psychopharmacology Bulletin Vol. 51 Iss. 2 (2021) p. 115 - 130 ISSN: 2472-2448 Available at: http://works.bepress.com/adam-kaye/139/