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Selected Works of Abid Shaikh
Article
Cinchona Alkaloid Induced Chiral Discrimination for the Determination of the Enantiomeric Composition of α-Trifluoromethylated Hydroxyl Compounds by 19F NMR Spectroscopy
Tetrahedron: Asymmetry (2005)
  • Abid Shaikh, Georgia Southern University
  • Béla Török
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Abstract
The determination of the enantiomeric composition of α-trifluoromethylated-hydroxyl compounds using cinchona alkaloids as chiral selectors is described. The interaction between the alkaloid and trifluoromethylated-hydroxyl compounds converted the enantiotopic nuclei to diastereotopic nuclei observed by 19F NMR spectroscopy. A wide variety of target molecules have been studied to highlight the broad applicability of the method.
Keywords
  • Of α-trifluoromethylated-hydroxyl,
  • Cinchona alkaloids,
  • NMR spectroscopy
Disciplines
Publication Date
2005
Citation Information
Abid Shaikh and Béla Török. "Cinchona Alkaloid Induced Chiral Discrimination for the Determination of the Enantiomeric Composition of α-Trifluoromethylated Hydroxyl Compounds by 19F NMR Spectroscopy" Tetrahedron: Asymmetry Vol. 16 Iss. 8 (2005)
Available at: http://works.bepress.com/abid_shaikh/17/