Acute cholecystitis is one of the most common reasons for acute surgical intervention in the emergency setting [1]. Rarely, pathological examination of the surgical specimen reveals incidental gallbladder cancer and even more infrequently metastasis of gallbladder from a distant site. We present a case of a patient with a known history of inflammatory breast carcinoma, who presented with symptoms of right upper quadrant pain and jaundice and diagnostic work- up consistent with acute cholecystitis, subsequently found to have metastatic breast cancer to the liver and gallbladder