There are a number of clinical options available for speech-language pathologists to choose from to analyze a child's phonological system, select treatment targets, and design intervention. Frequently, each of these areas of clinical options is viewed independently of one another or approached within an eclectic framework. In this article, an integrated and systemic approach is presented which assumes that a dynamic interaction exists among assessment, target selection, and intervention. Systemic Phonological Assessment of Child Speech, the distance metric approach to target selection, and the multiple oppositions treatment approach are described, with examples provided for each component. Finally, a case study is presented that examines the systemic approach of multiple oppositions relative to the approach of minimal pairs.