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volcano plot
Proteomics (2017)
  • Bennie Liu
Description
In statistics, a volcano plot is a kind of scatter plot that is applied to quickly seek out changes in large data sets composed of replicate data. It plots fold-change versus significance on the x and y axes, respectively. These plots are increasingly widely used in omic experiments such as genomics, transcriptomics, proteomics, and metabolomics where one usually has a long list of many thousands of replicate data points between two distinct conditions and one wants to quickly identify the most significant changes. A volcano plot combines a measure of statistical significance from a statistical test (e.g. a p value from an ANOVA model) with the magnitude changes, enabling quick visual determination of these data-points that represent large magnitude changes that are also statistically significant.
Keywords
  • volcano plot,
  • Statistical analysis,
  • bioinformatics service,
  • creative proteomics
Disciplines
Publication Date
Winter November 10, 2017
Citation Information
Bennie Liu. "volcano plot" Proteomics (2017)
Available at: http://works.bepress.com/Bioarray/6/