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Cytokines & Growth Factors
(2019)
  • Bennie Liu
Abstract
GROa is a member of the a (CXC) family of chemokines. It is produced by monocytes, neutrophils, mast cells, epithelial cells, endothelial cells, keratinocytes and tumor cells. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF. GROa is a chemoattractant for neutrophils, lymphocytes, monocytes, and epidermal melanocytes. In addition, GROa induces activation of neutrophils and basophils, has angiogenic effects, inhibits erythrocyte invasion and decreases the expression of interstitial collagen.
Keywords
  • Cytokines
Disciplines
Publication Date
Summer July 2, 2019
Citation Information
Bennie Liu. "Cytokines & Growth Factors" (2019)
Available at: http://works.bepress.com/Bioarray/111/