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Article
Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia
Biochemistry and Microbiology
  • Yoram Elitsur, MD, Marshall University
  • Deborah L. Preston, Joan C. Edwards School of Medicine, Marshall University
Document Type
Article
Publication Date
12-8-2016
Abstract

Objective: Vitamin D (Vit D) deficiency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the benefit of 2 months Vit D supplementation given to deficient obese children from WV.

Design: Vit D deficient obese children were prospectively recruited. Exclusion criteria included <8 years, and medical conditions that may affect Vit D homeostasis. Participants were randomized into two supplement groups: 5,000IU/day (Group A) or 50,000IU/week (Group B). Serum 25(OH)D levels were measured at baseline and post-treatment.

Results: Sixty obese children were screened of whom 39 (65%) were deficient (<20ng/ml). Of the 39 recruited, 26 completed the study. The mean serum 25(OH)D after 2 months treatment were significantly higher in Group B (p= 0.02), but most reached normal levels (>30ng/ml).

Conclusions: Two months Vit D supplementation (5000IU/day or 50,000IU/week) was sufficient to normalize 25(OH)D levels in Vit D deficient obese West Virginian children.

Comments

Copyright © 2016 Elitsur Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Citation Information
Elitsur Y, Preston DL (2016) Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia. Arch Clin Gastroenterol 2(1): 065-068. DOI: http://doi.org/10.17352/2455-2283.000024