Matricellular protein Cyr61 bridges lysophosphatidic acid and integrin pathways leading to cell migration (with D D. Wu, F Zhang, F Hao, J Chun, and M Z. Cui), The Journal of Biological Chemistry (2014)

Lysophosphatidic acid (LPA), a potent bioactive lipid found in atherosclerotic lesions, markedly induces smooth muscle...



LPA induces IL-6 secretion from aortic smooth muscle cells via an LPA1-regulated, PKC-dependent, and p38alpha-mediated pathway (with F Hao, M Tan, D Wu, and Mei-Zhen Cui), American journal of physiology. Heart and circulatory physiology (2010)

Lysophosphatidic acid (LPA) is a potent bioactive lysophospholipid. Accumulated evidence supports a role for LPA...



Residues at P2-P1 positions of epsilon- and zeta-cleavage sites are important in formation of beta-amyloid peptide (with Jianxin Tan, Guozhang Mao, Mei-Zhen Cui, Bruce Lamb, and Man-Sun Sy), Neurobiology of disease (2009)

Most of the Alzheimer's disease (AD)-linked mutations in amyloid precursor protein (APP), which cause abnormal...



Lysophosphatidylcholine activates a novel PKD2-mediated signaling pathway that controls monocyte migration (with M Tan, F Hao, GM Chisholm, and Mei-Zhen Cui), Arteriosclerosis, thrombosis, and vascular biology (2009)

OBJECTIVE: Monocyte activation and migration are crucial events in the development of atherosclerosis and other...



Gamma-secretase catalyzes sequential cleavages of the AbetaPP transmembrane domain, Journal of Alzheimer's disease : JAD (2009)

The biogenesis of the amyloid-beta peptide (Abeta) is a central issue in Alzheimer's disease (AD)...



Lysophosphatidic Acid, Tissue Factor and Atherosclerosis (invited commentary) (with Mei-Zhen Cui) (2003)