IN 2009, THE ASSOCIATION OF AMERICAN Medical Colleges (AAMC), in collaboration with the Howard Hughes Medical Institute (HHMI), reviewed the educational prerequisites for admission to medical school in the United States. Because a large fraction of undergraduate students enroll in science courses to meet the requirements for admission to medical school, courses satisfying these requirements dominate the undergraduate science curriculum. The prescribed course structure has impeded educational innovation, particularly the development of new, multidisciplinary courses. To address this situation, the AAMCHHMI report (1) recommends that scientific competencies replace specific courses as requirements for medical school admissions.