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Selected Works of Dr. Torstein Tengs
Article
Genomic representations using concatenates of type IIB restriction endonuclease digestion fragments
Nucleic Acids Research (2004)
  • Torstein Tengs, Dana-Farber Cancer Institute
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Abstract
We have developed a method for genomic representation using Type IIB restriction endonucleases. Representation by concatenation of restriction digests, or RECORD, is an approach to sample the fragments generated by cleavage with these enzymes. Here, we show that the RECORD libraries may be used for digital karyotyping and for pathogen identification by computational subtraction.
Disciplines
Publication Date
August, 2004
Citation Information
Tengs T, LaFramboise T, Den RB, Hayes DN, Zhang J, DebRoy S, Gentleman RC, O'Neill K, Birren B, Meyerson M. Genomic representations using concatenates of type IIB restriction endonuclease digestion fragments. Nucleic Acids Research 2004 Aug;32(15):e121.