Professional Interests -Dose adjustment in special animal populations or under special therapeutic conditions. Assessing the sources of variability in drug disposition and residue depletion in animal populations through the application of population pharmacokinetic and pharmacodynamic techniques. -Assessment of the risks associated with human exposure to environmental pollutants through the application of physiologically based pharmacokinetic and pharmacodynamic modeling. -Study of the association between drug exposure and the emergence of bacterial resistance in animal populations under different dosage regimen conditions. -Establishing information systems on antimicrobial use and the emergence of bacterial resistance in animal populations in Central America.
Animal Health Modeling & Simulation Society: a new society promoting model-based approaches in veterinary pharmacology (with J P. Mochel, J Gabrielsson, W Collard, M Fink, R Gehring, C Laffont, Y Liu, L Pelligrand, J L. Steimer, P L. Toutain, T Whittem, and J Riviere), Journal of Veterinary Pharmacology and Therapeutics (2013)
The Animal Health Modeling & Simulation Society (AHM&S) is a newly founded association (2012) that...
Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic, or palmar digital veins in standing horses (with J P. Mochel, J Gabrielsson, W Collard, M Fink, R Gehring, C Laffont, Y Liu, L Pelligand, J L. Steimer, P L. Toutain, T Whittem, and J Riviere), Journal of Veterinary Pharmacology and Therapeutics (2013)
There are no reported studies evaluating the use of erythromycin for regional limb perfusion (RLP)...
The role of the macrolide tulathromycin in veterinary medicine (with N Villarino and S A. Brown), Vet. J. (2013)
Tulathromycin is the first and only member of the triamilide sub-class of macrolides that is...
Evaluation of plasma diazepam and nordiazepam concentrations following administration of diazepam intravenously or via suppository per rectum in dogs (with C W. Probst, William B. Thomas, T D. Moyers, and Sherry Cox), American Journal of Veterinary Research (2013)
Pharmacokinetics of ponazuril after oral administration to healthy llamas (Lama glama). (with Maria E. Prado, J T. Ryman, M J. Boileau, and B Meibohm), American Journal of Veterinary Research (2011)
OBJECTIVE: To determine the pharmacokinetics after oral administration of a single dose of ponazuril to...
Contributions to Books
A Simple Case for Subdividing Populations Exposed to PCBs by Homologue Profile (with L. Hansen), PCBs: Human and Environmental Disposition and Toxicology (2008)
Toxicokinetic Extrapolation of PCB Exposure in Anniston, Alabama (with L. G. Hansen), PCBs: Human and Environmental Disposition and Toxicology (2008)
Pharmacokinetics I: Absorption and Distribution, Pharmacology and Therapeutics (2002)
Pharmacokinetics II: Metabolism, Excretion and Pharmacokinetic Models, Veterinary Pharmacology and Therapeutics (2002)