Professional Interests -Dose adjustment in special animal populations or under special therapeutic conditions. Assessing the sources of variability in drug disposition and residue depletion in animal populations through the application of population pharmacokinetic and pharmacodynamic techniques. -Assessment of the risks associated with human exposure to environmental pollutants through the application of physiologically based pharmacokinetic and pharmacodynamic modeling. -Study of the association between drug exposure and the emergence of bacterial resistance in animal populations under different dosage regimen conditions. -Establishing information systems on antimicrobial use and the emergence of bacterial resistance in animal populations in Central America.
Evaluation of plasma diazepam and nordiazepam concentrations following administration of diazepam intravenously or via suppository per rectum in dogs (with C W. Probst, William B. Thomas, T D. Moyers, and Sherry Cox), American Journal of Veterinary Research (2013)
Pharmacokinetics of Intravenous and Intramuscular Tramadol in Llamas (with Sherry Cox, Sarel R. Van Amstel, and Thomas Doherty), Journal of Veterinary Pharmacology and Therapeutics (2011)
The purpose of this study was to determine the pharmacokinetics of tramadol and its metabolite...
Pharmacokinetics of Oral Tramadol in Red-tailed Hawks (Buteo jamaicensis) (with Marcy J. Souza, Michael P. Jones, and Sherry K. Cox), Journal of Veterinary Pharmacology and Therapeutics (2011)
Determination of Carboplatin in Canine Plasma by High-performance Liquid Chromatography (with Nicolas Villarino, Sherry Cox, and Jason Yarbrough), Biomedical Chromatography (2010)
Carboplatin is an antineoplastic drug administered to treat different tumoral conditions in canine oncology. The...
Measurement of C-peptide Concentrations and Responses to Somatostatin, Glucose Infusion, and Insulin Resistance in Horses (with F. Toth, N. Frank, S. B. Elliott, R. J. Geor, and R. C. Boston), Equine Veterinary Journal (2010)
Reasons for performing study: Hyperinsulinaemia is detected in horses with insulin resistance (IR) and has...
Contributions to Books
A Simple Case for Subdividing Populations Exposed to PCBs by Homologue Profile (with L. Hansen), PCBs: Human and Environmental Disposition and Toxicology (2008)
Toxicokinetic Extrapolation of PCB Exposure in Anniston, Alabama (with L. G. Hansen), PCBs: Human and Environmental Disposition and Toxicology (2008)
Pharmacokinetics I: Absorption and Distribution, Pharmacology and Therapeutics (2002)
Pharmacokinetics II: Metabolism, Excretion and Pharmacokinetic Models, Veterinary Pharmacology and Therapeutics (2002)