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Fast Microtubule Dynamics in Meiotic Spindles Measured by Single Molecule Imaging: Evidence That the Spindle Environment Does Not Stabilize Microtubules (with D. J. Needleman, A. Groen, R. Ohi, L. Mirny, and T. Mitchison), Molecular Biology of the Cell (2010)
Metaphase spindles are steady-state ensembles of microtubules that turn over rapidly and slide poleward in...
Welcome to a new kind of tension: translating kinetochore mechanics into a wait-anaphase signal (with E. D. Salmon), Journal of Cell Science (2010)
Recent high-resolution studies of kinetochore structure have transformed the way researchers think about this crucial...
Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity (with E. D. Salmon), Journal of Cell Biology (2009)
Cells have evolved a signaling pathway called the spindle assembly checkpoint (SAC) to increase the...
Functional Overlap of Microtubule Assembly Factors in Chromatin-Promoted Spindle Assembly (with A. C. Groen, J. C. Gatlin, and E. D. Salmon), Molecular Biology of the Cell (2009)
Distinct pathways from centrosomes and chromatin are thought to contribute in parallel to microtubule nucleation...
Spindle Fusion Requires Dynein-Mediated Sliding of Oppositely Oriented Microtubules (with J. C. Gatlin, A. Maltov, A. C. Groen, D. J. Needleman, G. Danuser, T. J. Mitchison, and E. D. Salmon), Current Biology (2009)
Background Bipolar spindle assembly is critical for achieving accurate segregation of chromosomes. In the absence...