The vision of the Iowa NSF EPSCoR project “Harnessing Energy Flows in the Biosphere to Build Sustainable Energy Systems” is to establish Iowa as the leader in the world-wide transition in energy supply from mining subsurface (fossil) energy stores to harnessing renewable energy flows in the biosphere. The mission is to achieve organizational excellence, enhance Iowa’s research infrastructure, and prepare a diverse STEM educated workforce needed to advance Iowa’s competitive position in renewable energy and energy utilization. The research program is organized into four research platforms – BioEnergy, Wind Energy, Energy Utilization, and Energy Policy – and a Broader Impacts platform.