Articles
Memory T Cells Are Enriched in Lymph Nodes of Selectin-Ligand–Deficient Mice (with J. R. Harp and M. A. Gilchrist), Journal of Immunology (2010)
Fucosyltransferase-IV and -VII double knockout (FtDKO) mice reveal profound impairment in T cell trafficking to...
Both Systemic and Mucosal LCMV Immunization Generate Robust Viral-Specific IgG in Mucosal Secretions, But Elicit Poor LCMV-Specific IgA (with Bheemreddy Rajini, Junwei Zeng, Pratima Krishna Suvas, and Heather M. Dech), Viral Immunology (2010)
Immunoglobulins in secretions play a critical role in protection at mucosal surfaces. We examined the...
Naı¨ve T Cells Re-Distribute to the Lungs of Selectin Ligand Deficient Mice (with John R. Harp), PLoS One (2010)
BACKGROUND: Selectin mediated tethering represents one of the earliest steps in T cell extravasation into...
The generation of influenza-specific humoral responses is impaired in ST6Gal I-deficient mice. (with J Zeng, H. M. Joo, B. Rajini, J. P. Wrammert, and M. Y. Sangster), Journal of Immunology (2009)
Posttranslational modification of proteins, such as glycosylation, can impact cell signaling and function. ST6Gal I,...
Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis. (with P. Nagarajan, S. Rajagopalan, S. Kania, R. Donnell, and S. Venkatachalam), Oncogene (2009)
The chromodomain helicase DNA-binding proteins (CHDs) are known to affect transcription through their ability to...
Systemic and mucosal infection program protective memory CD8 T cells in the vaginal mucosa. (with P. K. Suvas, H. M. Dech, and J. Zeng), Journal of Immunology (2007)
Whether mucosal immunization is required for optimal protective CD8 T cell memory at mucosal surfaces...
Lack of antigen-specific tissue remodeling in mice deficient in the macrophage galactose-type calcium-type lectin 1/CD301a. (with K. Sato, Y. Imai, N. Higashi, Y. Kumamoto, S. M. Hedrick, and T. Irimura), Blood (2005)
Macrophage galactose-type C-type lectins (MGLs), which were recently named CD301, have 2 homologues in mice:...
CD43 modulates severity and onset of experimental autoimmune encephalomyelitis. (with M. L. Ford, A. Sperling, R. Ahmed, and B. D. Evavold), Journal of Immunology (2003)
Experimental autoimmune encephalomyelitis (EAE) is a mouse model of multiple sclerosis characterized by infiltration of...
Primary and Secondary Immunocompetence in Mixed Allogeneic Chimeras (with M. A. Williams, A. B. Adams, M. B. Walsh, N. Shirasugi, T. C. Pearson, R. Ahmed, and C. P. Larsen), The Journal of Immunology (2003)
Targeted disruption of T cell costimulatory pathways, particularly CD28 and CD40, has allowed for the...
TCR Signal Transduction in Antigen-Specific Memory CD8 T Cells (with Ellen N. Kersh, Susan M. Kaech, Miriana Moran, E. John Wherry, M. Carrie Miceli, and Rafi Ahmed), Journal of Immunology (2003)
Memory T cells are more responsive to Ag than naive cells. To determine whether memory...
Cutting Edge: Persistent Viral Infection Prevents Tolerance Induction and Escapes Immune Control Following CD28/CD40 Blockade-based Regimen (with M. A. Williams, A. B. Adams, M. M. Durham, T. C. Pearson, R. Ahmed, and C. P. Larsen), Journal of Immunology (2002)
A continuing concern with CD28 and/or CD40 blockade-based strategies to induce tolerance and mixed chimerism...
Molecular Cloning and Characterization of a Novel Mouse Macrophage C-type Lectin, mMGL2, Which Has a Distinct Carbohydrate Specificity from mMGL1 (with M. Tsuiji, M. Fujimori, Y. Ohashi, N. Higashi, S. M. Hendrick, and T. Irimura), Journal of Biological Chemistry (2002)
A novel mouse macrophage galactose-type C-type lectin 2 (mMGL2) was identified by BLAST analysis of...
Generation of Mice Deficient for Macrophage Galactose- and N-Acetylgalactosamine-Specific Lectin: Limited Role in Lymphoid and Erythroid Homeostasis and Evidence for Multiple Lectins (with M. Y. Lin, D. M. Page, S. A. Reynolds, C. D. Katayama, J. D. Marth, T. Irimura, A. Varki, N. Varki, and S. M. Hedrick), Molecular and Cellular Biology (2002)
Macrophage receptors function in pattern recognition for the induction of innate immunity, in cellular communication...
Dynamic Regulation of T Cell Immunity by CD43 (with L. E. Harrington, M. A. Williams, M. Galvan, C. P. Larsen, T. C. Pearson, N. Manjunath, L. G. Baum, B. D. Pearce, and R. Ahmed), Journal of Immunology (2002)
During a viral response, Ag-specific effector T cells show dramatically increased binding by the mAb...
Combinatorial Roles of the Nuclear Receptor Corepressor in Transcription and Development (with Kristen Jepsen, Ola Hermanson, Anatoli S. Anatoli S. Gleiberman, Victoria Lunyak, Robert J. McEvilly, Riki Kurokawa, Vivek Kumar, Forrest Liu, Edward Seto, Stephen M. Hedrick, Gail Mandel, Christopher K. Glass, David W. Rose, and Michael G. Rosenfeld), Cell (2000)
Transcriptional repression plays crucial roles in diverse aspects of metazoan development, implying critical regulatory roles...
Cellular and Biochemical Requirements for Thymocyte Negative Selection (with Dawn M. Page, Lawrence P. Kane, and Stephen M. Hedrick), Seminars in Immunology (1996)
Developing T cells which recognize self-proteins are specifically deleted by the process of negative selection...