The profound biologic, & societal burden of the syndrome of Diabetes Mellitus (DM) is subject of numerous ongoing research. There is significant interest in non-pharmacologic glycemic control, principally by exercise. While beneficial effects of generic exercise on glucose metabolism have been well established in literature, there is a paucity of research on the volume, intensity, & type of the most optimal forms of exercise that affect glycemic physiology in those with type II DM. The goal of this study was to perform a systematic review of the impact of high intensity interval training (HIIT) on glycemic control in people with type II DM. A systematic search using predefined keywords was performed on PubMed, CINAHL, PEDro, and Cochrane Register of Randomized Trials. Six studies met the inclusion criteria and were included in the review. The results of this study indicated that exercises have favorable effects on glycemic control in individuals with type II diabetes. The individuals who underwent HIIT experienced reduced glucose concentration, HbA1C level, systolic blood pressure, and BMI. However, the HIIT did not have any superior benefits when compared to the moderate intensity continuous exercise regime. In light of these findings, this review strongly recommends at least moderate intensity exercises, if not HIIT, in improving health outcomes in patients with type II DM.