Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Molecular defects in a human immunoglobulin kappa chain deficiency (with O. Kekish and B. J. Zegers), Science (New York, N.Y.) (1985)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Synthesis and isolation of DNA complementary to nucleotide sequences encoding the variable region of immunoglobulin kappa chain (with J. M. Bishop), Biochemistry (1977)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

PDF

Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

PDF

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Antibody class switching, Advances in immunology (1996)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities (with W. Lorenz, K. F. Schable, R. Thiebe, and H. G. Zachau), Molecular immunology (1988)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

PDF

Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

PDF

Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Link

Mechanism and regulation of class switch recombination (with Jeroen E. J. Guikema and Carol E. Schrader), Annual review of immunology (2008)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Antibody class switching: uncoupling S region accessibility from transcription (with Denise A. Kaminski), Trends in genetics : TIG (2004)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

Antibody class switching, Advances in immunology (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Regulation of antibody production and class switching by TGF-beta, Journal of immunology (Baltimore, Md. : 1950) (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities (with W. Lorenz, K. F. Schable, R. Thiebe, and H. G. Zachau), Molecular immunology (1988)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

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Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Molecular defects in a human immunoglobulin kappa chain deficiency (with O. Kekish and B. J. Zegers), Science (New York, N.Y.) (1985)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

PDF

Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

PDF

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Antibody class switching, Advances in immunology (1996)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Regulation of switch recombination to the murine gamma 1 gene (with W. Dunnick, L. Elenich, J. Berry, D. Albrecht, and J. L. Claflin), Current topics in microbiology and immunology (1992)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Immunoglobulin genes: generating diversity with AID and UNG (with Ursula Storb), Current biology : CB (2002)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities (with W. Lorenz, K. F. Schable, R. Thiebe, and H. G. Zachau), Molecular immunology (1988)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

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APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Antibody class switching: uncoupling S region accessibility from transcription (with Denise A. Kaminski), Trends in genetics : TIG (2004)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Triple helix stabilization, Nature (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Molecular genetics of immunoglobulin heavy chain switching, Survey of immunologic research (1983)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Antibody class switching, Advances in immunology (1996)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Regulation of switch recombination to the murine gamma 1 gene (with W. Dunnick, L. Elenich, J. Berry, D. Albrecht, and J. L. Claflin), Current topics in microbiology and immunology (1992)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

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Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

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Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Molecular genetics of immunoglobulin heavy chain switching, Survey of immunologic research (1983)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

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Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

Immunoglobulin genes: generating diversity with AID and UNG (with Ursula Storb), Current biology : CB (2002)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities (with W. Lorenz, K. F. Schable, R. Thiebe, and H. G. Zachau), Molecular immunology (1988)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Triple helix stabilization, Nature (1991)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

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Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Synthesis and isolation of DNA complementary to nucleotide sequences encoding the variable region of immunoglobulin kappa chain (with J. M. Bishop), Biochemistry (1977)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Link

Mechanism and regulation of class switch recombination (with Jeroen E. J. Guikema and Carol E. Schrader), Annual review of immunology (2008)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

PDF

Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

Molecular defects in a human immunoglobulin kappa chain deficiency (with O. Kekish and B. J. Zegers), Science (New York, N.Y.) (1985)

Synthesis and isolation of DNA complementary to nucleotide sequences encoding the variable region of immunoglobulin kappa chain (with J. M. Bishop), Biochemistry (1977)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

PDF

Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

PDF

Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Molecular defects in a human immunoglobulin kappa chain deficiency (with O. Kekish and B. J. Zegers), Science (New York, N.Y.) (1985)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

PDF

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Antibody class switching, Advances in immunology (1996)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Triple helix stabilization, Nature (1991)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities (with W. Lorenz, K. F. Schable, R. Thiebe, and H. G. Zachau), Molecular immunology (1988)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Synthesis and isolation of DNA complementary to nucleotide sequences encoding the variable region of immunoglobulin kappa chain (with J. M. Bishop), Biochemistry (1977)

Antibody class switching: uncoupling S region accessibility from transcription (with Denise A. Kaminski), Trends in genetics : TIG (2004)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Regulation of switch recombination to the murine gamma 1 gene (with W. Dunnick, L. Elenich, J. Berry, D. Albrecht, and J. L. Claflin), Current topics in microbiology and immunology (1992)

Immunoglobulin genes: generating diversity with AID and UNG (with Ursula Storb), Current biology : CB (2002)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Link

Mechanism and regulation of class switch recombination (with Jeroen E. J. Guikema and Carol E. Schrader), Annual review of immunology (2008)

PDF

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Antibody class switching: uncoupling S region accessibility from transcription (with Denise A. Kaminski), Trends in genetics : TIG (2004)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Immunoglobulin genes: generating diversity with AID and UNG (with Ursula Storb), Current biology : CB (2002)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Immunoglobulin class switching, Current opinion in immunology (1996)

Antibody class switching, Advances in immunology (1996)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Regulation of antibody production and class switching by TGF-beta, Journal of immunology (Baltimore, Md. : 1950) (1995)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of switch recombination to the murine gamma 1 gene (with W. Dunnick, L. Elenich, J. Berry, D. Albrecht, and J. L. Claflin), Current topics in microbiology and immunology (1992)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

Molecular defects in a human immunoglobulin kappa chain deficiency (with O. Kekish and B. J. Zegers), Science (New York, N.Y.) (1985)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Molecular genetics of immunoglobulin heavy chain switching, Survey of immunologic research (1983)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

PDF

Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Antibody class switching: uncoupling S region accessibility from transcription (with Denise A. Kaminski), Trends in genetics : TIG (2004)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Triple helix stabilization, Nature (1991)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

PDF

Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

PDF

Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Immunoglobulin class switching, Current opinion in immunology (1996)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Antibody class switching, Advances in immunology (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

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Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

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Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Molecular genetics of immunoglobulin heavy chain switching, Survey of immunologic research (1983)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

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Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

Triple helix stabilization, Nature (1991)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Regulation of antibody production and class switching by TGF-beta, Journal of immunology (Baltimore, Md. : 1950) (1995)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

Antibody class switching, Advances in immunology (1996)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

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Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Regulation of antibody production and class switching by TGF-beta, Journal of immunology (Baltimore, Md. : 1950) (1995)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Synthesis and isolation of DNA complementary to nucleotide sequences encoding the variable region of immunoglobulin kappa chain (with J. M. Bishop), Biochemistry (1977)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

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Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

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Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Molecular genetics of immunoglobulin heavy chain switching, Survey of immunologic research (1983)

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APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of switch recombination to the murine gamma 1 gene (with W. Dunnick, L. Elenich, J. Berry, D. Albrecht, and J. L. Claflin), Current topics in microbiology and immunology (1992)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

PDF

Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

Synthesis and isolation of DNA complementary to nucleotide sequences encoding the variable region of immunoglobulin kappa chain (with J. M. Bishop), Biochemistry (1977)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Link

Mechanism and regulation of class switch recombination (with Jeroen E. J. Guikema and Carol E. Schrader), Annual review of immunology (2008)

PDF

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Antibody class switching: uncoupling S region accessibility from transcription (with Denise A. Kaminski), Trends in genetics : TIG (2004)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Antibody class switching, Advances in immunology (1996)

Regulation of antibody production and class switching by TGF-beta, Journal of immunology (Baltimore, Md. : 1950) (1995)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Link

Mechanism and regulation of class switch recombination (with Jeroen E. J. Guikema and Carol E. Schrader), Annual review of immunology (2008)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Antibody class switching: uncoupling S region accessibility from transcription (with Denise A. Kaminski), Trends in genetics : TIG (2004)

Immunoglobulin genes: generating diversity with AID and UNG (with Ursula Storb), Current biology : CB (2002)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

PDF

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

Molecular defects in a human immunoglobulin kappa chain deficiency (with O. Kekish and B. J. Zegers), Science (New York, N.Y.) (1985)

PDF

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination (with Jeroen E. J. Guikema, Erin K. Linehan, Daisuke Tsuchimoto, Yusaku Nakabeppu, Phyllis R. Strauss, and Carol E. Schrader), The Journal of experimental medicine (2007)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Immunoglobulin genes: generating diversity with AID and UNG (with Ursula Storb), Current biology : CB (2002)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Inhibitors of poly(ADP-ribose) polymerase increase antibody class switching (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1993)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Regulation of switch recombination to the murine gamma 1 gene (with W. Dunnick, L. Elenich, J. Berry, D. Albrecht, and J. L. Claflin), Current topics in microbiology and immunology (1992)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Regulation of transcription of the germline immunoglobulin alpha constant region gene (with Y. C. Lin and P. Shockett), Current topics in microbiology and immunology (1992)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Mutations, duplication, and deletion of recombined switch regions suggest a role for DNA replication in the immunoglobulin heavy-chain switch (with W. Dunnick and M. Wilson), Molecular and cellular biology (1989)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Molecular genetics of immunoglobulin heavy chain switching, Survey of immunologic research (1983)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Genetic structure and origin of t haplotypes of mice, analyzed with H-2 cDNA probes (with H. S. Shin, K. Artzt, and D. Bennett), Cell (1982)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

PDF

Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities (with W. Lorenz, K. F. Schable, R. Thiebe, and H. G. Zachau), Molecular immunology (1988)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements (with Y. C. Lin), Journal of immunology (Baltimore, Md. : 1950) (1992)

Analysis of transforming growth factor-beta1-induced Ig germ-line gamma2b transcription and its implication for IgA isotype switching (with Seok-Rae Park, Goo-Young Seo, Ae-Jin Choi, and Pyeung-Hyeun Kim), European journal of immunology (2005)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation (with S. H. Waters and K. U. Saikh), Molecular and cellular biology (1989)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

The J kappa proximal region of the human K locus contains three uncommon V kappa genes which are arranged in opposite transcriptional polarities (with W. Lorenz, K. F. Schable, R. Thiebe, and H. G. Zachau), Molecular immunology (1988)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Molecular defects in a human immunoglobulin kappa chain deficiency (with O. Kekish and B. J. Zegers), Science (New York, N.Y.) (1985)

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Aberrant recombination events in B cell lines derived from a kappa-deficient human (with O. Kekish, D. Batter, J. Grenier, I. Balazs, E. Henderson, and B. J. Zegers), Nucleic acids research (1985)

Synthesis and isolation of DNA complementary to nucleotide sequences encoding the variable region of immunoglobulin kappa chain (with J. M. Bishop), Biochemistry (1977)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

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Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

File

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination (with Thomas M. Luby, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2001)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Regulation of switch recombination to the murine gamma 1 gene (with W. Dunnick, L. Elenich, J. Berry, D. Albrecht, and J. L. Claflin), Current topics in microbiology and immunology (1992)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes (with G. Radcliffe, Y. C. Lin, J. Nietupski, L. Berggren, R. Sitia, and E. Severinson), Proceedings of the National Academy of Sciences of the United States of America (1988)

Link

Mechanism and regulation of class switch recombination (with Jeroen E. J. Guikema and Carol E. Schrader), Annual review of immunology (2008)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Antibody class switching, Advances in immunology (1996)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Regulation of antibody production and class switching by TGF-beta, Journal of immunology (Baltimore, Md. : 1950) (1995)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Immunoglobulin genes: generating diversity with AID and UNG (with Ursula Storb), Current biology : CB (2002)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)

Evidence for class-specific factors in immunoglobulin isotype switching (with A. Shanmugam, M. J. Shi, L. Yauch, and A. L. Kenter), The Journal of experimental medicine (2000)

Molecular processes that regulate class switching, Current topics in microbiology and immunology (1999)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

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Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Surface immunoglobulin light-chain expression by the "common" all cell line REH (with B. Koziner and A. Al-Katib), Clinical immunology and immunopathology (1985)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Link

Mechanism and regulation of class switch recombination (with Jeroen E. J. Guikema and Carol E. Schrader), Annual review of immunology (2008)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Molecular genetics of immunoglobulin heavy chain switching, Survey of immunologic research (1983)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Copy choice mechanism of immunoglobulin heavy-chain switch recombination (with W. Dunnick), Molecular and cellular biology (1990)

Specificity of immunoglobulin heavy chain switching by cultured I.29 B lymphoma cells (with G. Radcliffe and E. Severinson), Monographs in allergy (1988)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction (with L. A. Iciek and S. A. Delphin), Journal of immunology (Baltimore, Md. : 1950) (1997)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50 (with S. Delphin), The Journal of experimental medicine (1995)

Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site (with M. Lundgren, C. Larsson, A. Femino, M. Xu, and E. Severinson), Journal of immunology (Baltimore, Md. : 1950) (1994)

I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch (with D. Klein, J. Nietupski, and S. Sirlin), Journal of immunology (Baltimore, Md. : 1950) (1988)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

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Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

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Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Roles of Ets proteins, NF-kappa B and nocodazole in regulating induction of transcription of mouse germline Ig alpha RNA by transforming growth factor-beta 1 (with M. J. Shi, S. R. Park, and P. H. Kim), International immunology (2001)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Letter: Translation of messenger RNA for mouse immunoglobulin light chains in living frog oocytes (with M. Smith, R. C. Huang, J. B. Gurdon, and C. D. Lane), Journal of molecular biology (1973)

Membrane-bound and secreted IgA contain structurally different alpha-chains (with R. Sitia, H. Kikutani, A. Rubartelli, Y. Bushkin, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1982)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins (with S. C. Lin and H. H. Wortis), Molecular and cellular biology (1998)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Mouse antibody response to group A streptococcal carbohydrate (with C. D. Jarvis and L. E. Cannon), Journal of immunology (Baltimore, Md. : 1950) (1989)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter (with M. J. Shi), Journal of immunology (Baltimore, Md. : 1950) (1998)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Effect of cytokines on switching to IgA and alpha germline transcripts in the B lymphoma I.29 mu. Transforming growth factor-beta activates transcription of the unrearranged C alpha gene (with P. Shockett), Journal of immunology (Baltimore, Md. : 1950) (1991)

Inducible DNA breaks in Ig S regions are dependent on AID and UNG (with Carol E. Schrader, Erin K. Linehan, Sofia N. Mochegova, and Robert T. Woodland), The Journal of experimental medicine (2005)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes (with Sean P. Bradley, Norman Rousseau, Todd Pearson, Ananth Shanmugam, Debra J. Waite, Paul R. Rogers, and Amy L. Kenter), Journal of immunology (Baltimore, Md. : 1950) (1999)

Overexpression of BSAP/Pax-5 inhibits switching to IgA and enhances switching to IgE in the I.29 mu B cell line (with G. Qiu), Journal of immunology (Baltimore, Md. : 1950) (1998)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

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Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes (with S. Sirlin and J. Abbott), The Journal of experimental medicine (1985)

Rearrangements and deletions of immunoglobulin heavy chain genes in the double-producing B cell lymphoma I.29 (with K. B. Marcu, S. Sirlin, B. Alhadeff, and U. Hammerling), Molecular and cellular biology (1982)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA (with Sean P. Bradley, Denise A. Kaminski, Antoine H. F. M. Peters, and Thomas Jenuwein), Journal of immunology (Baltimore, Md. : 1950) (2006)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Evolution of isotype switching (with Chris T. Amemiya), Seminars in immunology (2004)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA (with Elise E. Drouin, Carol E. Schrader, and Ulla Hansen), Journal of immunology (Baltimore, Md. : 1950) (2002)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Immunology. A touch of antibody class, Science (New York, N.Y.) (2000)

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice (with G. Qiu and G. R. Harriman), International immunology (1999)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Immunoglobulin class switching, Current opinion in immunology (1996)

Regulation of antibody class switching to IgE: characterization of an IL-4-responsive region in the immunoglobulin heavy-chain germline epsilon promoter (with S. Delphin), Annals of the New York Academy of Sciences (1995)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination (with Carol E. Schrader, Sean P. Bradley, Joycelyn Vardo, Sofia N. Mochegova, and Erin Flanagan), The EMBO journal (2003)

The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2 (with Irene M. Min, Carol E. Schrader, Joycelyn Vardo, Thomas M. Luby, Nicole D'Avirro, and Erik Selsing), Immunity (2003)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2002)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions (with Carol E. Schrader, Joycelyn Vardo, Erin K. Linehan, Michael Z. Twarog, Laura J. Niedernhofer, and Jan H. J. Hoeijmakers), The Journal of experimental medicine (2004)

Mlh1 can function in antibody class switch recombination independently of Msh2 (with Carol E. Schrader and Joycelyn Vardo), The Journal of experimental medicine (2003)

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes (with Carol E. Schrader, W. Edelmann, and R. Kucherlapati), The Journal of experimental medicine (1999)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Expression of an antigen receptor on T cells does not require recombination at the immunoglobulin JH-C mu locus (with Y. Cayre, M. A. Palladino, and K. B. Marcu), Proceedings of the National Academy of Sciences of the United States of America (1981)

Surface immunoglobulin light chain expression in pre-B cell leukemias (with B. Koziner, A. Al-Katib, D. Gebhard, A. Mittelman, M. Andreeff, and B. D. Clarkson), Annals of the New York Academy of Sciences (1986)

Regulation of antibody production and class switching by TGF-beta, Journal of immunology (Baltimore, Md. : 1950) (1995)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter (with J. Hanai, L. F. Chen, T. Kanno, N. Ohtani-Fujita, W. Y. Kim, W. H. Guo, T. Imamura, Y. Ishidou, M. Fukuchi, M. J. Shi, M. Kawabata, K. Miyazono, and Y. Ito), The Journal of biological chemistry (1999)

Interaction of stat6 and NF-kappaB: direct association and synergistic activation of interleukin-4-induced transcription (with Ching-Hung Shen), Molecular and cellular biology (1998)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes (with J. L. Lasky, N. M. Ponzio, M. P. Scheid, and G. J. Thorbecke), European journal of immunology (1989)

Mismatch repair converts AID-instigated nicks to double-strand breaks for antibody class-switch recombination (with Carol E. Schrader), Trends in genetics : TIG (2005)

Detection and characterization of RNA tumor virus-specific DNA in cells (with H. E. Varmus, E. Medeiros, and J. M. Bishop), Bibliotheca haematologica (1975)

Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes (with D. Sullivan, R. Palacios, J. M. Taylor, A. J. Faras, M. L. Kiely, N. M. Summers, J. M. Bishop, and R. T. Schimke), The Journal of biological chemistry (1973)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Regulation of the promoter for human immunoglobulin gamma3 germ-line transcription and its interaction with the 3'alpha enhancer (with Q. Pan, C. Petit-Frere, and L. Hammarstrom), European journal of immunology (2000)

Cognate T cell help for CD40-deficient B cells induces c-myc RNA expression, but DNA synthesis requires an additional signal through surface Ig (with Carol E. Schrader, H. Kikutani, and D. C. Parker), Journal of immunology (Baltimore, Md. : 1950) (1997)

Mouse CD6: sequence of cDNA and expression of mRNA (with A. Pal, P. L. Romain, N. G. Singer, and D. Fox), Immunology letters (1996)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination (with E. Severinson and C. Fernandez), European journal of immunology (1990)

Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes (with G. Radcliffe, Y. C. Lin, M. Julius, and K. B. Marcu), Molecular and cellular biology (1990)

Interleukins 4 and 5: mechanisms of action (with E. Severinson, H. B. Moon, S. Bergstedt-Lindqvist, U. Persson, and C. Heusser), Advances in experimental medicine and biology (1989)

Expression of immunoglobulin lambda light chain by the promyelocytic cell line HL-60 (with A. Al-Katib and B. Koziner), Journal of immunology (Baltimore, Md. : 1950) (1986)

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Presence of a polyadenylated RNA fragment encoding the membrane domain for immunoglobulin alpha chain indicates that mRNAs for both secreted and membrane-bound alpha chains can be produced from the same RNA transcript, Nucleic acids research (1986)

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching (with S. Sirlin), The EMBO journal (1986)

The regulation of membrane-bound and secreted alpha-chain biosynthesis during the differentiation of the B cell lymphoma I.29 (with R. Sitia, A. Rubartelli, H. Kikutani, and U. Hammerling), Journal of immunology (Baltimore, Md. : 1950) (1985)

Immunoglobulin heavy chain switching in cultured I.29 murine B lymphoma cells: commitment to an IgA or IgE switch (with J. Abbott and S. Sirlin), Current topics in microbiology and immunology (1984)

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Synthesis and processing of the alpha heavy chains of secreted and membrane-bound IgA (with H. Kikutani, R. Sitia, and R. A. Good), Proceedings of the National Academy of Sciences of the United States of America (1981)

Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse (with R. C. Huang, E. Stavnezer, and J. M. Bishop), Journal of molecular biology (1974)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2 (with Irene M. Min, Lisa R. Rothlein, Carol E. Schrader, and Erik Selsing), The Journal of experimental medicine (2005)

Does activation-induced deaminase initiate antibody diversification by DNA deamination (with Sean P. Bradley), Trends in genetics : TIG (2002)

Regulation of the antibody class switch to IgA (with Y. C. Lin and P. Shockett), Immunologic research (1991)

Structure of germline immunoglobulin heavy-chain gamma 1 transcripts in interleukin 4 treated mouse spleen cells (with M. Xu), Developmental immunology (1990)

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members (with M. Lundgren, L. Strom, L. O. Bergquist, S. Skog, T. Heiden, and E. Severinson), European journal of immunology (1995)

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter (with S. C. Lin), Molecular and cellular biology (1996)

Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer (with M. Z. Xu), The EMBO journal (1992)

Synthesis of a mouse immunoglobulin light chain in a rabbit reticulocyte cell-free system (with R. C. Huang), Nature: New biology (1971)

DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination (with Xiaoming Wu), The Journal of experimental medicine (2007)

Antibody class switching differs among SJL, C57BL/6 and 129 mice (with Denise A. Kaminski), International immunology (2007)

Stimuli that enhance IgA class switching increase histone 3 acetylation at S alpha, but poorly stimulate sequential switching from IgG2b (with Denise A. Kaminski), European journal of immunology (2006)

Enhanced IgA class switching in marginal zone and B1 B cells relative to follicular/B2 B cells (with Denise A. Kaminski), Journal of immunology (Baltimore, Md. : 1950) (2006)

Differential regulation of mouse germline Ig gamma 1 and epsilon promoters by IL-4 and CD40 (with C. S. Mao), Journal of immunology (Baltimore, Md. : 1950) (2001)

Activation of the mouse Ig germline epsilon promoter by IL-4 is dependent on AP-1 transcription factors (with Ching-Hung Shen), Journal of immunology (Baltimore, Md. : 1950) (2000)