(99m)Tc-DTPA Diuretic Renal Scintigraphy in Dogs with Nephroureterolithiasis
This study evaluated the results of diuretic renal scintigraphy in dogs with urolithiasis. Eighty-three kidneys with nephroureterolithiasis +/- renal pelvis/ureteral dilation were included in the study. Sixty-three kidneys showed a non-obstructive pattern, with a steep drop or gradual downward slope of renal time-activity curve (TAC). Excretion half-time of radiopharmaceutical (T(1/2)) was 3.99 (2.99 to 7.95) min. Three kidneys showed an obstructive pattern, with continuous rise of the TAC and median T(1/2) of -10.71 (-5.20 to -17.56) min. Fifteen kidneys had non-diagnostic studies characterized by flat TAC. Individual kidney glomerular filtration rate was <0.5 mL/min/kg body weight in most non-diagnostic studies. Diuretic renal scintigraphy appears to be a useful adjunct modality to rule out or confirm ureteral obstruction in dogs. Additional diagnostic procedures may be necessary to achieve a definitive diagnosis in cases of severely impaired renal function.
Silke Hecht, Meg S. Lawson, India F. Lane, Dorothy E. Sharp, and Gregory B. Daniel. "(99m)Tc-DTPA Diuretic Renal Scintigraphy in Dogs with Nephroureterolithiasis" The Canadian Veterinary Journal. La Revue Vétérinaire Canadienne 51.2 (2010): 1360-1366.
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