Dr. Choudhary’s research focuses on the identification of molecular targets of novel anticancer agents (Histone deacetylase inhibitors) for developing targeted therapy against human bladder, breast, and colon cancer. His research also involves the identification of preventive agents to prevent the development and progression of sporadic breast cancer caused by prolonged exposure to various environmental and dietary carcinogens. Dr. Choudhary received his DVM-equivalent professional degree from the College of Veterinary Medicine & Animal Sciences, Kerala Agricultural University, India in June, 2004, and PhD degree in Molecular Oncology from the College of Veterinary Medicine, the University of Tennessee, USA in May, 2009. He is currently doing his postdoctoral research training in the field of Cancer Biology at the University of Tennessee.
Articles
Intervention of human breast cell carcinogenesis chronically induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (with Hwa-Chain R. Wang, Shilpa Sood, and Robert L. Donnell), Carcinogenesis (2012)
More than 85% of breast cancers are sporadic and attributable to long-term exposure to environmental...
Dipyridamole intervention of breast cell carcinogenesis (with Shilpa Sood and Hwa-Chain Robert Wang), Molecular Carcinogenesis (2012)
Dietary prevention is a cost-efficient strategy to reduce the risk of human cancers. More than...
Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. (with Kusum Rathore, Agricola Odoi, and Hwa-Chain Robert Wang), Carcinogenesis (2012)
Long-term exposure to low doses of environmental carcinogens contributes to sporadic human breast cancers. Epidemiologic...
Oncogenic H-Ras, FK228, and exogenous H2O2 cooperatively activated the ERK pathway in selective induction of human urinary bladder cancer J82 cell death (with K-KA Wang and H-CR Wang), Molecular Carcinogenesis (2011)
More than 35% of human urinary bladder cancers involve oncogenic H-Ras activation. The goal of...
Differential induction of reactive oxygen species through Erk1/2 and Nox-1 by FK228 for selective apoptosis of oncogenic H-Ras-expressing human urinary bladder cancer J82 cells (with Kusum Rathore and H. C. Wang), Journal of Cancer Research and Clinical Oncology (2011)
PURPOSE: This study sought to reveal mechanisms for differential regulation of reactive oxygen species (ROS)...